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exogenous human recombinant angptl7 protein  (R&D Systems)


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    R&D Systems exogenous human recombinant angptl7 protein
    Expressions of four angiogenesis-related genes post-MI. (A) Volcano plot showing log2 fold-change of total gene expression in MI mice 4 days post-MI, compared with sham-operated mice. Genes that were significantly increased in MI group ( n = 3) compared with sham group ( n = 4) are highlighted on red, while those decreased are highlighted in green. (B) Ang , Vegfd , Angptl4 and <t>Angptl7</t> were four angiogenesis-related upregulated genes (* P < 0.05). Bar graph revealed that Angptl7 was the most significantly upregulated member among the four genes.
    Exogenous Human Recombinant Angptl7 Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/exogenous+human+recombinant+angptl7+protein/pmc12550588-137-8-13?v=R%26D+Systems
    Average 93 stars, based on 2 article reviews
    exogenous human recombinant angptl7 protein - by Bioz Stars, 2026-08
    93/100 stars

    Images

    1) Product Images from "Associations of angiopoietin-like protein 7 with coronary collateral circulation and prognosis of patients with severe coronary artery stenosis"

    Article Title: Associations of angiopoietin-like protein 7 with coronary collateral circulation and prognosis of patients with severe coronary artery stenosis

    Journal: Frontiers in Cardiovascular Medicine

    doi: 10.3389/fcvm.2025.1559267

    Expressions of four angiogenesis-related genes post-MI. (A) Volcano plot showing log2 fold-change of total gene expression in MI mice 4 days post-MI, compared with sham-operated mice. Genes that were significantly increased in MI group ( n = 3) compared with sham group ( n = 4) are highlighted on red, while those decreased are highlighted in green. (B) Ang , Vegfd , Angptl4 and Angptl7 were four angiogenesis-related upregulated genes (* P < 0.05). Bar graph revealed that Angptl7 was the most significantly upregulated member among the four genes.
    Figure Legend Snippet: Expressions of four angiogenesis-related genes post-MI. (A) Volcano plot showing log2 fold-change of total gene expression in MI mice 4 days post-MI, compared with sham-operated mice. Genes that were significantly increased in MI group ( n = 3) compared with sham group ( n = 4) are highlighted on red, while those decreased are highlighted in green. (B) Ang , Vegfd , Angptl4 and Angptl7 were four angiogenesis-related upregulated genes (* P < 0.05). Bar graph revealed that Angptl7 was the most significantly upregulated member among the four genes.

    Techniques Used: Gene Expression

    The associations between serum ANGPTL7 levels and CCC. (A) Comparison of serum ANGPTL7 levels among three groups. (B) Scatter plot of serum ANGPTL7 levels and the Rentrop score. (C) ROC curve for serum ANGPTL7 in the prediction of good CCC. CI, confidence interval; *** P < 0.001.
    Figure Legend Snippet: The associations between serum ANGPTL7 levels and CCC. (A) Comparison of serum ANGPTL7 levels among three groups. (B) Scatter plot of serum ANGPTL7 levels and the Rentrop score. (C) ROC curve for serum ANGPTL7 in the prediction of good CCC. CI, confidence interval; *** P < 0.001.

    Techniques Used: Comparison

    Elevated serum ANGPTL7 in both patients with SCS and post-infarct mice. (A) Comparison of serum ANGPTL7 levels of patients with ≤50% coronary stenosis and ≥90% stenosis by ELISA. (B) Comparison of serum ANGPTL7 levels of mice in the sham and the MI group by ELISA. *** P < 0.001.
    Figure Legend Snippet: Elevated serum ANGPTL7 in both patients with SCS and post-infarct mice. (A) Comparison of serum ANGPTL7 levels of patients with ≤50% coronary stenosis and ≥90% stenosis by ELISA. (B) Comparison of serum ANGPTL7 levels of mice in the sham and the MI group by ELISA. *** P < 0.001.

    Techniques Used: Comparison, Enzyme-linked Immunosorbent Assay

    The prognostic performance of serum ANGPTL7 for patients with SCS. (A) Comparison of serum ANGPTL7 levels of patients in the poor and the good prognosis group. (B) Kaplan–Meier survival curves for MACE between different levels of serum ANGPTL7 according to the median concentration. (C) Time-dependent ROC curves of serum ANGPTL7 for the prediction of MACE. AUC, area under the curve; CI, confidence interval; *** P < 0.001.
    Figure Legend Snippet: The prognostic performance of serum ANGPTL7 for patients with SCS. (A) Comparison of serum ANGPTL7 levels of patients in the poor and the good prognosis group. (B) Kaplan–Meier survival curves for MACE between different levels of serum ANGPTL7 according to the median concentration. (C) Time-dependent ROC curves of serum ANGPTL7 for the prediction of MACE. AUC, area under the curve; CI, confidence interval; *** P < 0.001.

    Techniques Used: Comparison, Concentration Assay

    The enhanced endothelial cell proliferation, migration and capillary-like structure formation induced by exogenous ANGPTL7. (A) Representative images of scratch assays (40× magnification, scan bar = 500 μm). (B) Comparison of scratch healing rates [=(0 h scratch width-24 h scratch width)/0 h scratch width × 100%] between the exogenous ANGPTL7 group and PBS group (three independent experiments were performed, * P < 0.05). (C) Cell viabilities (=the relative ratio of cell number) in CCK8 assays were compared between the two groups (three independent experiments were performed, ** P < 0.01). (D) Representative images of tube formation assays (10× magnification, scan bar = 100 μm). (E) Number of master junctions was calculated and compared between the two groups (three independent experiments were performed, * P < 0.05).
    Figure Legend Snippet: The enhanced endothelial cell proliferation, migration and capillary-like structure formation induced by exogenous ANGPTL7. (A) Representative images of scratch assays (40× magnification, scan bar = 500 μm). (B) Comparison of scratch healing rates [=(0 h scratch width-24 h scratch width)/0 h scratch width × 100%] between the exogenous ANGPTL7 group and PBS group (three independent experiments were performed, * P < 0.05). (C) Cell viabilities (=the relative ratio of cell number) in CCK8 assays were compared between the two groups (three independent experiments were performed, ** P < 0.01). (D) Representative images of tube formation assays (10× magnification, scan bar = 100 μm). (E) Number of master junctions was calculated and compared between the two groups (three independent experiments were performed, * P < 0.05).

    Techniques Used: Migration, Comparison

    The proangiogenic property of ANGPTL7. (A) Representative images of cell immunofluorescence assays (40× magnification, scan bar = 50 μm, VE-cadherin expression region exhibits green fluorescence). (B) VE-cadherin expression was detected and quantified by immunofluorescence after 24-h stimulation by exogenous human recombinant ANGPTL7 protein, compared with PBS as control (three independent experiments were performed, *** P < 0.001). (C) Representative images of western blot detecting protein levels of ANGPTL7, VE-cadherin, Claudin18, MMP-2, VEGFR2 and internal control β-actin in HUVECs. Western blot analysis was performed to compare the protein levels of ANGPTL7 (D) , VE-cadherin (E) , Claudin18 (F) , MMP-2 (G) and VEGFR2 (H) between the two groups (three independent experiments were performed, * P < 0.05, ** P < 0.01, *** P < 0.001).
    Figure Legend Snippet: The proangiogenic property of ANGPTL7. (A) Representative images of cell immunofluorescence assays (40× magnification, scan bar = 50 μm, VE-cadherin expression region exhibits green fluorescence). (B) VE-cadherin expression was detected and quantified by immunofluorescence after 24-h stimulation by exogenous human recombinant ANGPTL7 protein, compared with PBS as control (three independent experiments were performed, *** P < 0.001). (C) Representative images of western blot detecting protein levels of ANGPTL7, VE-cadherin, Claudin18, MMP-2, VEGFR2 and internal control β-actin in HUVECs. Western blot analysis was performed to compare the protein levels of ANGPTL7 (D) , VE-cadherin (E) , Claudin18 (F) , MMP-2 (G) and VEGFR2 (H) between the two groups (three independent experiments were performed, * P < 0.05, ** P < 0.01, *** P < 0.001).

    Techniques Used: Immunofluorescence, Expressing, Fluorescence, Recombinant, Control, Western Blot



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    exogenous human recombinant angptl7 protein  (R&D Systems)
    93
    R&D Systems exogenous human recombinant angptl7 protein
    Expressions of four angiogenesis-related genes post-MI. (A) Volcano plot showing log2 fold-change of total gene expression in MI mice 4 days post-MI, compared with sham-operated mice. Genes that were significantly increased in MI group ( n = 3) compared with sham group ( n = 4) are highlighted on red, while those decreased are highlighted in green. (B) Ang , Vegfd , Angptl4 and <t>Angptl7</t> were four angiogenesis-related upregulated genes (* P < 0.05). Bar graph revealed that Angptl7 was the most significantly upregulated member among the four genes.
    Exogenous Human Recombinant Angptl7 Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/exogenous+human+recombinant+angptl7+protein/pmc12550588-137-8-13?v=R%26D+Systems
    Average 93 stars, based on 1 article reviews
    exogenous human recombinant angptl7 protein - by Bioz Stars, 2026-08
    93/100 stars
    		  Buy from Supplier

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    Expressions of four angiogenesis-related genes post-MI. (A) Volcano plot showing log2 fold-change of total gene expression in MI mice 4 days post-MI, compared with sham-operated mice. Genes that were significantly increased in MI group ( n = 3) compared with sham group ( n = 4) are highlighted on red, while those decreased are highlighted in green. (B) Ang , Vegfd , Angptl4 and Angptl7 were four angiogenesis-related upregulated genes (* P < 0.05). Bar graph revealed that Angptl7 was the most significantly upregulated member among the four genes.

    Journal: Frontiers in Cardiovascular Medicine

    Article Title: Associations of angiopoietin-like protein 7 with coronary collateral circulation and prognosis of patients with severe coronary artery stenosis

    doi: 10.3389/fcvm.2025.1559267

    Figure Lengend Snippet: Expressions of four angiogenesis-related genes post-MI. (A) Volcano plot showing log2 fold-change of total gene expression in MI mice 4 days post-MI, compared with sham-operated mice. Genes that were significantly increased in MI group ( n = 3) compared with sham group ( n = 4) are highlighted on red, while those decreased are highlighted in green. (B) Ang , Vegfd , Angptl4 and Angptl7 were four angiogenesis-related upregulated genes (* P < 0.05). Bar graph revealed that Angptl7 was the most significantly upregulated member among the four genes.

    Article Snippet: HUVECs in the experimental group were treated with exogenous human recombinant ANGPTL7 protein (R&D Systems, 914-AN) at a final concentration of 1 μg/ml for 24 h, whereas cells in the control group received an equivalent volume of PBS.

    Techniques: Gene Expression

    The associations between serum ANGPTL7 levels and CCC. (A) Comparison of serum ANGPTL7 levels among three groups. (B) Scatter plot of serum ANGPTL7 levels and the Rentrop score. (C) ROC curve for serum ANGPTL7 in the prediction of good CCC. CI, confidence interval; *** P < 0.001.

    Journal: Frontiers in Cardiovascular Medicine

    Article Title: Associations of angiopoietin-like protein 7 with coronary collateral circulation and prognosis of patients with severe coronary artery stenosis

    doi: 10.3389/fcvm.2025.1559267

    Figure Lengend Snippet: The associations between serum ANGPTL7 levels and CCC. (A) Comparison of serum ANGPTL7 levels among three groups. (B) Scatter plot of serum ANGPTL7 levels and the Rentrop score. (C) ROC curve for serum ANGPTL7 in the prediction of good CCC. CI, confidence interval; *** P < 0.001.

    Article Snippet: HUVECs in the experimental group were treated with exogenous human recombinant ANGPTL7 protein (R&D Systems, 914-AN) at a final concentration of 1 μg/ml for 24 h, whereas cells in the control group received an equivalent volume of PBS.

    Techniques: Comparison

    Elevated serum ANGPTL7 in both patients with SCS and post-infarct mice. (A) Comparison of serum ANGPTL7 levels of patients with ≤50% coronary stenosis and ≥90% stenosis by ELISA. (B) Comparison of serum ANGPTL7 levels of mice in the sham and the MI group by ELISA. *** P < 0.001.

    Journal: Frontiers in Cardiovascular Medicine

    Article Title: Associations of angiopoietin-like protein 7 with coronary collateral circulation and prognosis of patients with severe coronary artery stenosis

    doi: 10.3389/fcvm.2025.1559267

    Figure Lengend Snippet: Elevated serum ANGPTL7 in both patients with SCS and post-infarct mice. (A) Comparison of serum ANGPTL7 levels of patients with ≤50% coronary stenosis and ≥90% stenosis by ELISA. (B) Comparison of serum ANGPTL7 levels of mice in the sham and the MI group by ELISA. *** P < 0.001.

    Article Snippet: HUVECs in the experimental group were treated with exogenous human recombinant ANGPTL7 protein (R&D Systems, 914-AN) at a final concentration of 1 μg/ml for 24 h, whereas cells in the control group received an equivalent volume of PBS.

    Techniques: Comparison, Enzyme-linked Immunosorbent Assay

    The prognostic performance of serum ANGPTL7 for patients with SCS. (A) Comparison of serum ANGPTL7 levels of patients in the poor and the good prognosis group. (B) Kaplan–Meier survival curves for MACE between different levels of serum ANGPTL7 according to the median concentration. (C) Time-dependent ROC curves of serum ANGPTL7 for the prediction of MACE. AUC, area under the curve; CI, confidence interval; *** P < 0.001.

    Journal: Frontiers in Cardiovascular Medicine

    Article Title: Associations of angiopoietin-like protein 7 with coronary collateral circulation and prognosis of patients with severe coronary artery stenosis

    doi: 10.3389/fcvm.2025.1559267

    Figure Lengend Snippet: The prognostic performance of serum ANGPTL7 for patients with SCS. (A) Comparison of serum ANGPTL7 levels of patients in the poor and the good prognosis group. (B) Kaplan–Meier survival curves for MACE between different levels of serum ANGPTL7 according to the median concentration. (C) Time-dependent ROC curves of serum ANGPTL7 for the prediction of MACE. AUC, area under the curve; CI, confidence interval; *** P < 0.001.

    Article Snippet: HUVECs in the experimental group were treated with exogenous human recombinant ANGPTL7 protein (R&D Systems, 914-AN) at a final concentration of 1 μg/ml for 24 h, whereas cells in the control group received an equivalent volume of PBS.

    Techniques: Comparison, Concentration Assay

    The enhanced endothelial cell proliferation, migration and capillary-like structure formation induced by exogenous ANGPTL7. (A) Representative images of scratch assays (40× magnification, scan bar = 500 μm). (B) Comparison of scratch healing rates [=(0 h scratch width-24 h scratch width)/0 h scratch width × 100%] between the exogenous ANGPTL7 group and PBS group (three independent experiments were performed, * P < 0.05). (C) Cell viabilities (=the relative ratio of cell number) in CCK8 assays were compared between the two groups (three independent experiments were performed, ** P < 0.01). (D) Representative images of tube formation assays (10× magnification, scan bar = 100 μm). (E) Number of master junctions was calculated and compared between the two groups (three independent experiments were performed, * P < 0.05).

    Journal: Frontiers in Cardiovascular Medicine

    Article Title: Associations of angiopoietin-like protein 7 with coronary collateral circulation and prognosis of patients with severe coronary artery stenosis

    doi: 10.3389/fcvm.2025.1559267

    Figure Lengend Snippet: The enhanced endothelial cell proliferation, migration and capillary-like structure formation induced by exogenous ANGPTL7. (A) Representative images of scratch assays (40× magnification, scan bar = 500 μm). (B) Comparison of scratch healing rates [=(0 h scratch width-24 h scratch width)/0 h scratch width × 100%] between the exogenous ANGPTL7 group and PBS group (three independent experiments were performed, * P < 0.05). (C) Cell viabilities (=the relative ratio of cell number) in CCK8 assays were compared between the two groups (three independent experiments were performed, ** P < 0.01). (D) Representative images of tube formation assays (10× magnification, scan bar = 100 μm). (E) Number of master junctions was calculated and compared between the two groups (three independent experiments were performed, * P < 0.05).

    Article Snippet: HUVECs in the experimental group were treated with exogenous human recombinant ANGPTL7 protein (R&D Systems, 914-AN) at a final concentration of 1 μg/ml for 24 h, whereas cells in the control group received an equivalent volume of PBS.

    Techniques: Migration, Comparison

    The proangiogenic property of ANGPTL7. (A) Representative images of cell immunofluorescence assays (40× magnification, scan bar = 50 μm, VE-cadherin expression region exhibits green fluorescence). (B) VE-cadherin expression was detected and quantified by immunofluorescence after 24-h stimulation by exogenous human recombinant ANGPTL7 protein, compared with PBS as control (three independent experiments were performed, *** P < 0.001). (C) Representative images of western blot detecting protein levels of ANGPTL7, VE-cadherin, Claudin18, MMP-2, VEGFR2 and internal control β-actin in HUVECs. Western blot analysis was performed to compare the protein levels of ANGPTL7 (D) , VE-cadherin (E) , Claudin18 (F) , MMP-2 (G) and VEGFR2 (H) between the two groups (three independent experiments were performed, * P < 0.05, ** P < 0.01, *** P < 0.001).

    Journal: Frontiers in Cardiovascular Medicine

    Article Title: Associations of angiopoietin-like protein 7 with coronary collateral circulation and prognosis of patients with severe coronary artery stenosis

    doi: 10.3389/fcvm.2025.1559267

    Figure Lengend Snippet: The proangiogenic property of ANGPTL7. (A) Representative images of cell immunofluorescence assays (40× magnification, scan bar = 50 μm, VE-cadherin expression region exhibits green fluorescence). (B) VE-cadherin expression was detected and quantified by immunofluorescence after 24-h stimulation by exogenous human recombinant ANGPTL7 protein, compared with PBS as control (three independent experiments were performed, *** P < 0.001). (C) Representative images of western blot detecting protein levels of ANGPTL7, VE-cadherin, Claudin18, MMP-2, VEGFR2 and internal control β-actin in HUVECs. Western blot analysis was performed to compare the protein levels of ANGPTL7 (D) , VE-cadherin (E) , Claudin18 (F) , MMP-2 (G) and VEGFR2 (H) between the two groups (three independent experiments were performed, * P < 0.05, ** P < 0.01, *** P < 0.001).

    Article Snippet: HUVECs in the experimental group were treated with exogenous human recombinant ANGPTL7 protein (R&D Systems, 914-AN) at a final concentration of 1 μg/ml for 24 h, whereas cells in the control group received an equivalent volume of PBS.

    Techniques: Immunofluorescence, Expressing, Fluorescence, Recombinant, Control, Western Blot